Senior Chemist
Job # 1628
CordenPharma Colorado


CordenPharma Colorado
CordenPharma Colorado is a highly sophisticated and entrepreneurial mid-sized pharmaceutical manufacturing company located in Boulder, Colorado. Our chemists and engineers are widely recognized for their history of innovation, having developed efficient manufacturing processes for some of the world's most complex pharmaceutical compounds. CordenPharma Colorado also is acclaimed for its flexible manufacturing facilities and experienced workforce that can handle a wide range of production techniques and volumes. Ultimately, in partnership with our customers, CordenPharma Colorado is focused on its health care mission, proudly producing medicines that help patients around the globe survive and enjoy more comfortable lives.                                                              


Acts to drive and demonstrate the technology for the planning and execution of development and implementation of chemical processes.  Ensures that the chemistry is sufficient to meet goals on process yields, throughputs and QEH&S requirements.  Is an expert on poly-arginine peptides.

ESSENTIAL DUTIES AND RESPONSIBILITIES include the following. Other duties may be assigned.

  • Executes experiments and syntheses of small molecules and peptides while working on a project team.
  • Performs peptide synthesis using commercial peptide synthesizers.
  • Has direct knowledge in the synthesis of poly-arginine peptides.  In particular, experience with the poly-arginine peptide, Novamycin is required.
  • Performs preparative-scale chromatography in a lab environment.Conducts analyses of samples using established or routine methods.
  • Provides technical support to lab or plant processes.
  • Works effectively in a team-oriented environment
  • Presents work orally and in form of written development reports
  • Adheres to cGMP and SOPs in all aspects of work
  • Independently plans and executes experiments, while working in a project team, toward development of viable commercial processes.
  • Demonstrates a clear understanding of technical issues and the requirements of a viable manufacturing process.
  • Executes procedures, processes and methods for solutions to chemical and technical problems on a lab or plant scale.
  • Ensures that the chemistry is capable of meeting cost, yield, throughput and QEH&S goals on assigned processes.
  • Leads a team to accomplish the development, transfer or implementation of technology at a lab or plant scale.
  • Develops and supports scalable processes and provides technical expertise and support during lab or plant operations.  


This job has no supervisory responsibilities.


Every individual is personally responsible for the safety and environmental aspects of his or her activities in the workplace.  Each employee is expected to perform their job duties in a safe manner utilizing all of their knowledge, training, ability and experience.


To perform this job successfully, an individual must be able to perform each essential duty satisfactorily. The requirements listed below are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.


Bachelor’s degree (BS) in organic chemistry and at least 5 years related experience and/or training; or equivalent combination of education and experience. Demonstrated competence in Design of Experiments and statistical data analysis as applied in multiple projects preferred.


Ability to read, analyze, and interpret common scientific and technical journals, financial reports, and legal documents. Ability to respond to common inquiries or complaints from customers, regulatory agencies, or members of the business community. Ability to develop bench scale laboratory procedures into step by step operating instructions for chemical operators. Ability to effectively present information to top management, public groups, and/or boards of directors.


Ability to apply advanced mathematical concepts such as exponents, logarithms, quadratic equations, and permutations.  Ability to apply mathematical operations to such tasks as frequency distribution, determination of test reliability and validity, analysis of variance, correlation techniques, sampling theory, and factor analysis.


Ability to apply principles of logical or scientific thinking to a wide range of intellectual and practical problems.  Ability to deal with nonverbal symbolism (formulas, scientific equations, graphs, etc.,) in its most difficult phases.  Ability to deal with a variety of abstract and concrete variables.  Ability to apply scientific methods to experimentally prove cause and effect.


Domestic and international travel required.


The physical demands described here are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
While performing the duties of this job, the employee is regularly required to talk or hear.  The employee frequently is required to stand, walk, and sit.  The employee must occasionally lift and/or move up to 25 pounds.  Specific vision abilities required by this job include close vision, distance vision, and color vision.


The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.  Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
While performing the duties of this job, the employee is occasionally exposed to moving mechanical parts, fumes or airborne particles, low levels of toxic or caustic chemicals, outside weather conditions, and vibration.   The noise level in the work environment is usually moderate.

These are the specific areas of knowledge, skill and ability that are important for successful job performance. They must be job related and consistent with business necessity.
  • Demonstrates a positive attitude.
  • Strong background in chemistry or a related scientific field.
  • Working knowledge of regulatory issues in pharmaceutical manufacturing including cGMPs, PSM, OSHA and EPA requirements.
  • Communicates effectively in writing and verbally within the department.
  • Computer skills, in the areas of: Microsoft Office Products – Word, Excel, PowerPoint.
  • Ability to work interactively within a multi-functional team-oriented environment.
  • Takes initiative in setting own goals and work plan
  • Hands on organic chemistry laboratory experience
  • Has broad technical knowledge in organic chemistry and process improvement methodology
  • Maintain a well documented record of work performed in a laboratory notebook, laboratory reports, and campaign reports
  • Experience in the synthesis and purification of peptides (desired)
  • Has working knowledge of all plant-scale unit operations, scale-up, and plant design considerations;
  • Understanding of chemical reactivity, potential exotherms, cross reactivity, side products and waste streams, especially for processes he/she supports
  • Regularly seeks out new learning opportunities beyond basic skills that can result in innovative approaches to technical issues
  • Demonstrates clear understanding of technical issues and the requirements of a viable manufacturing process; has demonstrated independent support on multiple (not necessarily simultaneous) processes
  • Identifies areas where change /continuous improvement is beneficial to the business, and successfully defends and implements projects
  • Assumes reasonable risk in trying out new, self-generated ideas
  • Proactive approach to problem identification and resolution.
  • Communicates effectively in writing and verbally within and across departments and to site management; updates are clear, selective and effective
  • Ability to understand and apply statistical design of experiments and draw sound conclusions from the results; uses results when solving problems, or proposing improvements
  • Ability to provide leadership in all process chemistry aspects of manufacturing processes; leads teams in the development, transfer, trouble-shooting, and improvement of chemical processes in interactive, interdisciplinary team environment.
  • Seeks out opportunities to learn manufacturing needs and methods that facilitates substantial process improvements; acquires new skills in state-of-the art technology and applies it to their assignments
  • Demonstrates skills in negotiation and influencing others
This is a non-exempt position. Salary based upon the successful candidate’s qualifications and level of experience.


Please refer to: Job #1628 – Senior Chemist.  
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