CordenPharma Colorado Facility Capacities

Technologies / Processes

  • Hydrogenation / Hydrogenolysis
  • Cryogenic chemistry
  • Pyrophoric chemistry
  • Chiral chemistry
  • Pegylation chemistry
  • Pre-formulated liquid products
  • Peptides
  • Peptide synthesis (10,000 L)
  • Cyclization (up to 12,000 L)
  • De-aggregation chemistry (Pseudoprolines, DMB)
  • Ion exchange ( size exclusion chromatography)
  • Ultrafiltration, Diafiltration
  • Precipitation of peptides ( allows larger batches)
  • High Pressure preparative chromatography (up to 1M diameter)
  • Lab equipment design (mimics plant design)

Equipment Details

  • Large-scale
  • Pilot plant
  • Peptide purification
  • Highly active compounds

Capacities

  • One of the largest vessel capacities in the API Contract Manufacturing arena
  • Nearly 470,000 L vessel volume available

Other Specialties

Current APIs
  • Enfuvirtide
  • Valcyte
  • Cytovene
  • Linaclotide
  • Rocaltrol
  • Highly Active Peptide A
  • Protease Inhibitor Intermediate