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LNP Summit 2025: Development & Optimization of TFF Purification for Lipid Nanoparticles

Presented at our LNP Summit Boston – Sept 9, 2025
by Dr. Umberto Romeo, Global Head of Development: Injectables & LNPs, CordenPharma Caponago

Dr. Umberto Romeo, CordenPharma’s Global Head of Development for LNPs & Injectables, shares strategies to improve LNP purification during early development. His talk addresses:

🔹 Approaches to optimizing TFF (Tangential Flow Filtration) purification

🔹 Key challenges in meeting the desired Quality Target Product Profile (QTPP)

🔹 Ensuring particle integrity, effective scale‑up, and high purity

🔹 Innovative methods implemented to streamline purification workflows

 

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